Why study worms? Click here to learn more about why C. elegans is a powerful model system.
We study three major events, all of which occur in virtually all animal embryos:
(1) Polarized cell motility during dorsal intercalation, a directed cell rearrangement
(2) Actin networks during ventral enclosure, an example of epithelial sheet sealing
(3) The cadherin complex and mobilization of the actin cytoskeleton at cell-cell junctions
(4) How actin networks repair and maintain cell shape change during elongation.
We have also developed some microscopy techniques that have broad applications.
Our work is supported by the National Institute of General Medical Sciences, NIH (current award #R35 GM145312).
