Why study worms? Click here to learn more about why C. elegans is a powerful model system.
We study three major events, all of which occur in virtually all animal embryos:
(1) Polarized cell motility during dorsal intercalation, a directed cell rearrangement
(2) Actin networks during ventral enclosure, an example of epithelial sheet sealing
(3) The cadherin complex and mobilization of the actin cytoskeleton at cell-cell junctions
(4) How actin networks repair and maintain cell shape change during elongation.
We have also developed some microscopy techniques that have broad applications.